Development Pipeline

Kyntra Bio is dedicated to creating innovative, first-in-class medicines for the treatment of chronic, life-threatening, and debilitating conditions, such as mCRPC and anemia associated with LR-MDS.

Our investigational products are not limited to single indications—they represent broader therapeutic platforms designed to target key biological pathways and mediators involved in multiple diseases. This approach enables us to pursue high-impact opportunities across a range of conditions with shared molecular drivers.

Clinical development pipeline showing Kyntra Bio investigational products by development phase Clinical development pipeline showing Kyntra Bio investigational products by development phase

Roxadustat

Roxadustat is the first oral HIF-PH inhibitor to be approved and launched globally. It promotes erythropoiesis, or red blood cell production, by stimulating endogenous erythropoietin production, enhancing iron absorption and mobilization, and downregulating of hepcidin.

Pill being shaken out of a pill bottle
Healthcare providers discussion Kyntra Bio clinical trial information

FG-3246 + FG-3180

FG-3246 is a potential first-in-class, fully human ADC targeting CD46. It is currently in Phase 2 development for mCRPC and has the potential for additional trials targeting additional CD46-expressing cancers. As part of the program, Kyntra Bio is also developing FG-3180, a CD46-targeted PET imaging agent designed to support patient selection by identifying CD46-positive lesions.